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Botox injection is the most commonly performed non-surgical cosmetic procedure.

Despite being colloquially known as snake venom, Botulinum Toxin (Botox) is actually a toxin secreted by the bacterium that is medically referred to as «Clostridium Botulinum». The poisoning condition caused by this bacterium is referred to as «botulism». Its existence has been known since the late 19th century. Botulism took place in literature in that period of history, for the first time. Botox that leads to botulism is the most powerful known neurotoxin.

The first usage area of Botox that began to be used in the field of medicine in the early 1980 is strabismus treatment. In 1986, dermatologist Dr. Alastair Carruthers observed that Botox applied by his wife Jean Carruthers, an ophthalmologist, to her patients for the treatment of strabismus also diminished the wrinkles around the eyes. As of that date, wrinkles have been treated with Botox. Afterwards, Botox has quickly been included in the usage area of neurology. It is used successfully in the treatment of Dystonia (a group of diseases causing involuntary movements in many parts of the body including the face).

What is the Mechanism of Action of Botox ?

When injected into the muscle, Botox eliminates the involuntary movements and excessive contractions by temporarily deactivating the nerves of that muscle or muscle groups. The effect of Botox applied lasts for a period of 2 to 7 days. The mentioned temporary effect lasts 3 to 4 months, and contractions may start again at the end of this period. Therefore, the injections need to be repeated.

How to Apply Botox ?

Small amounts of Botox are injected into the desired area, using fine needles. By means of such needles, it acts by blocking the communication between the nerves and the organs that the nerves reach. Botox relaxes the muscle by blocking the nerve impulses for a certain time; and consequently, enables the skin to get stretched and leads the elimination of wrinkles.

Its most common area of use is the elimination of forehead wrinkles and crow’s feet. The eyebrows can be lifted with Botox, to a certain extent. Very thin and superficial wrinkles in the upper lip (smoking lines) can be improved. The nasal tip of some people moves when laughing and talking. Such a movement can be prevented with Botox. It can be applied to the palms, soles, and armpits, to prevent perspiration.

What are the Applications Areas ?

1-Cosmetic Application Areas

* Upper/Middle/Lower Face
  • Softening the Wrinkles in the Forehead
  • Softening the Frown Lines
  • Lifting the Droopy Eyebrows
  • Softening the Wrinkles at the Sides of the Eyes (Crow’s Feet)
  • Softening the Lines on the Nose (Bunny Lines)
  • Nasal Tip Lifting
  • Smoking Lines
  • Chin Wrinkles (the appearance of orange peel)
* Neck
  • Relaxing the Platysmal Muscles
*Calf Thinning

2. Usage Areas Other than the Ones Within the Scope of Cosmetic Applications

  • Migraines and Headaches
  • Involuntary Contraction of Neck Muscles (Torticollis)
  • Involuntary Contraction of the Muscles Around the Eye and at Its sides
  • Cramps Emerging in the Fingers When Writing
  • Contractions of the Masseter (Chin Muscle), and Teeth Grinding
  • Sudden Involuntary Tics (Dystonia, Spasticity)
  • Excessive Sweating (Hyperhidrosis)
  • Involuntary Leakage of Urine Unresponsive to Medication (Idiopathic Overactive Bladder or Neurogenic Detrusor Overactivity)
  • Anal Fissure

Who Should not Get Botox Injection ?

It can be used safely in both sexes, as from the age of two. However, drugs like aminoglycosides that have an effect on neuromuscular transmission in myasthenia gravis, amyotrophic lateral sclerosis, and pregnancy should not be used in breastfeeding period or in people who has been given Botulinum Neurotoxin for another reason.

What are the Side Effects of Botox ?

Botox has been used for 25 years in the service of medicine, for the treatment of many diseases. It is a quite safe drug. It does not cause significant side effects, or even if it does, we know that the effect is temporary. The most common side effect is the spread of Botox to non-targeted muscles, followed by the temporary weakness of those muscles. For example, in case of its overdose, the eyelid problem referred to as “ptosis” may emerge, and it causes the patient to feel discomfort for several weeks. Therefore, since the muscles in the facial region are smaller, particularly the dosages applied to the face are very important. This treatment approach gives quite beatific results, in the hands of physicians who have received the training required for applying Botox.